Enhancing Cardiovascular Risk Prediction through Deep Learning Analysis of Chest Radiographs

ERDEM YANAR
Middle East Technical University, ASELSAN INC


Abstract

The rapid advancement in deep learning technologies has paved the way for significant enhancements in medical imaging analysis, particularly in diagnosing and predicting the risk of cardiovascular diseases (CVDs) from chest radiographs. This study introduces a novel deep learning framework that leverages convolutional neural networks (CNNs) to estimate cardiovascular risk from chest X-ray images, offering a potentially transformative tool for early CVD detection and management. Utilizing a dataset of over 10,000 annotated chest radiographs, our model was trained to identify and quantify key radiographic features associated with increaseardiovascular risk, such as cardiac silhouette enlargement, aortic calcifications, and d cpulmonary congestion.

The proposed model underwent extensive validation against a gold-standard reference, including echocardiographic findings and clinical cardiovascular outcomes. Our results demonstrate the model's remarkable accuracy, with an area under the receiver operating characteristic curve (AUC) of 0.92, surpassing traditional risk prediction models. Furthermore, the deep learning model showed high specificity and sensitivity in identifying patients at high risk of cardiovascular events, indicating its potential to serve as a valuable screening tool in clinical settings.

In conclusion, our work underscores the efficacy of deep learning in extracting clinically relevant information from chest radiographs, a widely available yet underutilized resource in cardiovascular risk stratification. By automating the detection of subtle radiographic markers of CVD risk, our model promises to enhance the predictive capabilities of clinicians, leading to earlier intervention and improved patient outcomes. Future research directions include the integration of this model into clinical workflows and the investigation of its impact on patient management strategies, particularly in resource-limited settings where advanced imaging modalities may not be readily available.