A regional characterization of conduction velocity (CV) could help to understand the specific pathophysiology of atrial fibrillation (AF) in each patient, allowing a greater degree of personalization of ablation strategies and increasing their success rate. Regional characterization from low spatial resolution intracavitary electrical recordings with basket catheter (electrode spacing 6-10 mm) was compared to high-resolution mapping with grid catheter (electrode spacing 2-3 mm). A robust multi-approach method was used to measure CVs in recordings obtained during AF episodes in 5 patients (72 ± 8 years) with both recording systems. In N=222 measurements, 74% of the CV estimation obtained with low-resolution mapping presented an error of less than 150 mm/s with respect to closest high-resolution mapping estimation. CV maps obtained with the low-resolution mapping showed similar regional variations as those obtained from the grid, limited to their respective spatial resolutions, and were able to reproduce the inter-patient variability. Estimation of regional CV during AF can be obtained from both high- and low-resolution mapping catheters, with reproducible outcomes, which can be a promising tool for therapy personalization.