As a routine standard-of-care test, an electrocardiogram (ECG) provides primary indicators of pathology. This study aims to assess the effect of scar location on ECG morphology. The left ventricle of an anatomically accurate biventricular tetrahedral mesh was divided into 17 segments according to the American Heart Association (AHA). The myocardial wall was divided into endocardium, mid-myocardium and epicardium, each layer taking up 33% of the wall thickness. In addition, an endocardial layer (up to 80% of the endocardium) was determined in both ventricles to act as a surrogate for the Purkinje network. Sequentially, each of the 17 regions and their three transmural layers were set as non-conductive to mimic myocardial scar. The biventricular mesh was inserted inside a torso, and the 12-lead ECGs were simulated for each scenario. A reference ECG was obtained from a mesh with all 17 AHA segments being set as conductive for comparison. Two stimulation methods were tested and compared. Each region being tested for 4 scar cases (endocardium, mid-myocardium, epicardium and whole wall) show fluctuation in the shape of the QRS complex compared to the reference no scar ECG. Scars in the mid-myocardium or in the whole cardiac wall were the most impactful. Root mean square error of ECGs associated with mid-myocardial and fully transmural scars are the least similar across all leads. The precordial leads are the most affected and apical scars have the highest impact on ECG signal perturbation. Our approach helps link ECG morphology to scar location and transmurality: fully transmural and mid-myocardial scars visibly alter the ECG, while epicardial and endocardial scars in most regions have minimal impact. Moreover, varying the scar location, size and number could help in creating an atlas map for scar effects.